Biocompatibility of hemodialysis membranes.

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Biocompatibility of hemodialysis membranes.

Exposure of blood to hemodialysis membranes results in numerous interactions between the blood elements and the membrane. Transformation and adsorption of plasma proteins (such as complement) and activation of blood cells (such as neutrophils and monocytes) have been studied most extensively by nephrologists in recent years. There is no consensus on the definition of biocompatibility for dialyz...

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Maintenance hemodialysis patients display evidence of elevated interleukin-1 (IL-1) and tumor necrosis factor alpha release after stimulation either by contaminated dialysate, bioincompatible membrane material, or both. This release is followed by the stimulated secretion of a large number of other interleukins, particularly IL-6, the cytokine principally responsible for acute-phase protein syn...

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ژورنال

عنوان ژورنال: Journal of the American Society of Nephrology

سال: 1990

ISSN: 1046-6673,1533-3450

DOI: 10.1681/asn.v12150